Though our expertly crafted guide to L.A. Noire may be invaluable, there's one group who may still be struggling: Those living with Asperger's syndrome. Though the autism-spectrum disorder leaves cognitive and linguistic functions relatively preserved, it leaves some with what's sometimes referred to as mind-blindness, or the inability to divine what's happening in the mind of another human. In the words of researcher and coiner of the phrase Simon Baron-Cohen, those with mind-blindness find they have an inability to "put themselves into someone else's shoes, to imagine their thoughts and feelings."

In L.A. Noire, facial animations are so realistically captured that players can actually tell if their interview subjects are lying. In fact, players have to do precisely that to unearth the clues essential to putting a case together.

As we progressed through the game, we worried that could leave those with mind-blindness unable to play along, especially if the technology is more widely adopted. But where we saw a hurdle, Professor Tony Attwood sees opportunity.